Journal of medicinal chemistry

Irreversible enzyme inhibitors. 195. Inhibitors of thymidine kinase from Walker 256 carcinoma derived from thymidine 5'-acetate

BR Baker, JP Neenan

文献索引：Baker,B.R.; Neenan,J.P. Journal of Medicinal Chemistry, 1972 , vol. 15, # 9 p. 940 - 944

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被引用次数: 13

摘要

Seventeen derivatives of thymidine 5'-carbamate and 27 5'-esters of thymidine were synthesized an! investigated as inhibitors of thymidine kinase from Walker 256 rat tumor. Derivatives of thymidine 5-acetate were good inhibitors of the enzyme. The inhibition ...