Synthesis and biological evaluation of all eight stereoisomers of DPP-IV inhibitor saxagliptin

J Dong, Y Gong, J Liu, X Chen, X Wen, H Sun

文献索引：Bioorganic and Medicinal Chemistry, , vol. 22, # 4 p. 1383 - 1393

全文：HTML全文

被引用次数: 5

摘要

... Bioorganic & Medicinal Chemistry. ... Moreover, as potential impurities of saxagliptin API (Active Pharmaceutical Ingredient), the synthesis of stereoisomers 1b–1h is highly desirable to provide the reference substances for drug quality control. ...