Discovery of 2-aminothiazole-4-carboxamides, a novel class of muscarinic M3 selective antagonists, through solution-phase parallel synthesis

Y Sagara, M Mitsuya, M Uchiyama, Y Ogino…

文献索引：Chemical and Pharmaceutical Bulletin, , vol. 53, # 4 p. 437 - 440

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被引用次数: 12

摘要

... Chemistry Preparation of 3f was outlined in Chart 1 as a representa- tive procedure for ... Tsukuba Research Institute, Banyu Pharmaceutical Co., Ltd.; Okubo-3, Tsukuba, Ibaraki 300-2611, Japan. ... carboxamide derivative (1) as a lead compound in our in-house chemical collection ...