Process development for ABT-472, a benzimidazole PARP inhibitor

JH Barkalow, J Breting, BJ Gaede…

文献索引：Organic Process Research and Development, , vol. 11, # 4 p. 693 - 698

被引用次数: 20

摘要

... Organic Process Research & Development. ... The process was successfully scaled up to provide 8.5 kg of final product of >99% purity in 33% yield ... 13 Calorimetry during the direct addition procedure showed an exotherm of −140 kJ/mol, consistent with the calculated exotherm for ...

641-70-3

3-硝基邻苯二甲酸酐

603-11-2

3-硝基邻苯二甲酸

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