Synthesis

Development of a Robust and Practical Process for the Darzens Condensation and α, β-Epoxide Rearrangement: Scope and Limitations of the Methodology

JM Zimbron, M Seeger-Weibel, H Hirt, F Gallou

文献索引：Synthesis, , # 8 p. 1221 - 1226

全文：HTML全文

被引用次数: 2

摘要

... The process developed is both amenable to large scale and parallel synthesis. ... 8, ... The Darzens condensation of p-cyano-substituted benzaldehyde with (±)-2-chloropropionic acid methyl ester was therefore conducted under a variety of dehydrating conditions (molecular sieves ...