Preparation and regiospecific cyclization of alkenyllithiums

WF Bailey, TT Nurmi, JJ Patricia…

文献索引：Bailey,W.F.; Nurmi,T.T.; Patricia,J.J. Journal of the American Chemical Society, 1987 , vol. 109, p. 2442

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被引用次数: 106

摘要

Abstract: A two-step, one-pot sequence has been developed that provides an anionic route to functionalized carbocycles containing five-or six-membered rings. Primary alkenyllithiums, which are prepared in excellent yield by metal-halogen interchange between the appropriate iodide and t-BuLi at-78 OC, are stable at low temperature. These species have been found to undergo regiospecific, and in several instances totally stereoselective, ...