Tetrahedron Letters

Specificity of E. coli shikimate dehydrogenase towards analogues of 3-dehydroshikimic acid

TDH Bugg, C Abell, JR Coggins

文献索引：Bugg, Timothy D. H.; Abell, Chris; Coggins, John R. Tetrahedron Letters, 1988 , vol. 29, # 51 p. 6779 - 6782

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被引用次数: 18

摘要

Abstract Analogues of 3-dehydroshikimic acid which lack the C-4 and C-5 hydroxyl groups have been synthesised and assayed as substrates for shikimate dehydrogenase. The presence of the C-4 hydroxyl group is found to be very important for specificity, whereas ...