Synthetic communications

A Convenient Synthesis of 2??Acylphenylacetonitriles

AS Cánepa, RD Bravo

文献索引：Canepa, Alicia S.; Bravo, Rodolfo D. Synthetic Communications, 2004 , vol. 34, # 4 p. 579 - 588

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被引用次数: 5

摘要

The reaction of 2??cyanomethylbenzoyl chloride with Grignard reagents in the presence of cuprous iodide at −5°C easily affords 2??acylphenylacetonitriles with good yield. ... The reaction of 2??cyanomethylbenzoyl chloride with Grignard reagents in the presence of cuprous iodide at −5°C easily affords 2??acylphenylacetonitriles with good yield. ... View all references Only few examples for the synthesis of 2??acylphenylacetonitriles are reported in the literature.55. Watt , DS 1976. A reiterative functionalization of ...