The reaction of 2??cyanomethylbenzoyl chloride with Grignard reagents in the presence of cuprous iodide at −5°C easily affords 2??acylphenylacetonitriles with good yield. ... The reaction of 2??cyanomethylbenzoyl chloride with Grignard reagents in the presence of cuprous iodide at −5°C easily affords 2??acylphenylacetonitriles with good yield. ... View all references Only few examples for the synthesis of 2??acylphenylacetonitriles are reported in the literature.55. Watt , DS 1976. A reiterative functionalization of ...
