Tricyclic potential neuroleptics: 2-chloro-11-[4-(4-fluoroaralkyl) piperazino]-10, 11-dihydrodibenzo [b, f] thiepins and related compounds

V Bártl, A Dlabač, M Protiva

文献索引：Bartl; Dlabac; Protiva Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 11 p. 3182 - 3189

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被引用次数: 5

摘要

Abstract Alkylation of 1-ethoxycarbonylpiperazine with 4-fluorobenzyl bromide, 2-(4- fluorophenyl) ethyl bromide and 4, 4-bis (4-fluorophenyl) butyl bromide gave the carbamates IIa, IIb and IIf. Two further similar compounds (IIc, IId) were obtained by reactions of 1-(2- chloroethyl)-4-ethoxycarbonylpiperazine with 4-fluorophenol, and with 4-fluorothiophenol, respectively. Hydrolysis of carbamates IIa-f resulted in piperazine derivatives IIIa-f ...