Nickel??Mediated Inter??and Intramolecular Reductive Cross??Coupling of Unactivated Alkyl Bromides and Aryl Iodides at Room Temperature

…, Y Peng, XB Xu, YW Wang

文献索引：Yan, Chang-Song; Peng, Yu; Xu, Xiao-Bo; Wang, Ya-Wen Chemistry - A European Journal, 2012 , vol. 18, # 19 p. 6039 - 6048

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被引用次数: 55

摘要

Abstract A nickel-mediated intermolecular reductive cross-coupling reaction of unactivated alkyl bromides and aryl iodides at room temperature has been developed and successfully extended to less explored intramolecular versions and tandem cyclization-intermolecular cross-coupling. Highly stereoselective (or stereospecific) synthesis of linear-fused perhydrofuro [2, 3-b] furan (pyran) and spiroketal skeletons allows rapid access to these ...