Standard hydrogenation conditions: A solution of 2 (500 mg, 1.17 mmol) in MeOH (7.5 mL) was degassed with nitrogen for 15 min. A sample of (−)-1,2-Bis((2R, 5R)-2,5-dimethylphospholano )benzene(cyclooctadiene)rhodium (I) trifluoromethanesulfonate (7.5 mg, 0.011 mmol, purchased from STREM) was charged and the sample was hydrogenated (40 psi H 2 ) at 20°C for 24 h. The crude solution was filtered through silica gel (2:1 ethyl acetate/hexane) to remove the ...
