Thermal cleavage of the Fmoc protection group

…, R Marti, R Riedl, M Simeunovic

文献索引：Hoeck, Stefan; Marti, Roger; Riedl, Rainer; Simeunovic, Marina Chimia, 2010 , vol. 64, # 3 p. 200 - 202

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被引用次数: 5

摘要

The Fmoc protection group is among the most commonly used protection groups for the amino function. A fast method for the thermal deavage of this protection group under base- free conditions without the need for dibenzofulvene scavengers is presented. The advantages of this method include straightforward testability by means of a simple high- temperature NMR experiment, usually high yields, and good selectivity towards the BOC ...