7-Azaindole derivatives may be considered as useful indole bioisosteres in medicinal chemistry and functionalization at C-2 and C-3 of the 7-azaindole ring system is well described in the scientific literature. Substitution of the pyrrole ring has been effected either directly on the 7-azaindole core or, alternatively, by cyclization of a requisite pyridine precursor. 1 On the other hand, the limited number of examples of 4-, 5-, and 6-substituted 7-azaindoles reported thus far ...
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