... DOI: 10.1039/C2DT32429F (Paper) Dalton Trans., 2013, 42, 2023-2034 ... d Calculated by VolSurf+; definitions: PB = percentage of protein binding, VD = distribution volume [l kg −1 ], CACO2 = qualitative value of cells permeability, lgBB = logarithm of the blood–brain ...