Applied Catalysis A: General

Reinvestigating Raney nickel mediated selective alkylation of amines with alcohols via hydrogen autotransfer methodology

A Mehta, A Thaker, V Londhe, SR Nandan

文献索引：Mehta, Astha; Thaker; Londhe; Nandan, Santosh R. Applied Catalysis A: General, 2014 , vol. 478, p. 241 - 251

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被引用次数: 6

摘要

Abstract An efficient, cost-effective use of Raney nickel (R-Ni) a widely used industrial catalyst for N-alkylation using alcohols is highlighted here. The work describes the scope and capability of R-Ni in hydrogen autotransfer reactions enabling its widespread use in the Chemical and Pharmaceutical industry. R-Ni of W4, T4, and W7 grades were prepared and evaluated for alkylation of amines. The best activity and selectivity for mono alkylation of ...