The Journal of organic chemistry

Concise Approach to Benzisothiazol-3 (2 H)-one via Copper-Catalyzed Tandem Reaction of o-Bromobenzamide and Potassium Thiocyanate in Water

F Wang, C Chen, G Deng, C Xi

文献索引：Wang, Fei; Chen, Chao; Deng, Geng; Xi, Chanjuan Journal of Organic Chemistry, 2012 , vol. 77, # 8 p. 4148 - 4151

被引用次数: 38

摘要

A concise approach to various benzisothiazol-3 (2 H)-one derivatives has been developed by copper-catalyzed the reaction of o-bromobenzamide derivatives with potassium thiocyanate (KSCN) in water. The reaction proceeds via a tandem reaction with S–C bond and S–N bond formation.

349403-39-0

N-丁基2-溴苯甲酰胺

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~60%

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~48%

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~45%

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~60%

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~35%

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