Synthesis

Improved procedure for palladium-catalyzed Hiyama cross-coupling reaction of aryl halides with aryltrimethoxysilanes under solvent-free conditions

JH Li, CL Deng, YX Xie

文献索引：Li, Jin-Heng; Deng, Chen-Liang; Xie, Ye-Xiang Synthesis, 2006 , # 6 p. 969 - 974

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被引用次数: 18

摘要

Abstract An improved palladium-catalyzed Hiyama cross-coupling reaction is reported. In the presence of PdCl 2 (MeCN) 2, P (o-tol) 3 and TBAF, a number of ArX (X= I, Br, Cl) were coupled with ArSi (OMe) 3 efficiently to afford the desired cross-coupled products in moderate to excellent yields. It is noteworthy that this protocol is conducted under relatively low Pd loadings and solvent-free conditions.