A simple synthesis of aminopyridines: use of amides as amine source

A Kodimuthali, A Mungara, PL Prasunamba…

文献索引：Kodimuthali, Arumugam; Mungara, Anitha; Prasunamba, Padala Lakshmi; Pal, Manojit Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 8 p. 1439 - 1445

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被引用次数: 10

摘要

2-Aminopyridine derivatives, though well known for a long time, have attracted considerable interest recently because of their applications in various fields especially in pharmaceutical research. For example, the use of 2-aminopyridines have been reported as glucokinase activators 1 or selective inhibitors of neuronal nitric oxide synthase. 2 Substituted or unsubstituted aminopyridines are also useful precursors for the synthesis of a variety of heteocyclic compounds ...