Substituted 2, 3-Dihydro-1, 5-benzothiazepin-4 (5H)-ones and 3, 4-Dihydro-2-phenyl-(2H)-1, 6-benzothiazocin-5 (6H)-ones

J Krapcho, ER Spitzmiller, CF Turk

文献索引：Krapcho,J. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 544 - 546

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被引用次数: 57

摘要

The sjntliesis of substituted 2,3-dilij dro-1,5-bcn~:otlii~zepiri-4~.5H)-oncs :ind thtxir alkylation is described. Tlie preparation of 3,4-dili~dro-2-pl1enyl-2H-l,6-benzotliiti~o~in-~(6H)-ori~~ ... 111 extension of our studies on substituted 2-phenyl- 1 ,~-beiixothiaxiii-3(4H)-oiies, we have prepared a number of related 2,3-dihydro-l..',-benzothiazepin-4 (,iH)-oiies (Table 11) and :3,~-dihpdro-'-plieiiyl-2H-l,fi- 1)ciizot hiaxociii-5 (GI3)-ones. The iiiteriiiediate 2,;2-dililvdro-l ...