Microwave??Promoted “One??Pot” Synthesis of 4??Nitrobenzylthioinosine Analogues Using Thiourea as a Sulfur Precursor

…, GR Qu, S Wu, Y Jiang, X Jin, HM Guo

文献索引：Niu, Hong-Ying; Xia, Chao; Qu, Gui-Rong; Wu, Shan; Jiang, Yi; Jin, Xin; Guo, Hai-Ming Chemistry - An Asian Journal, 2012 , vol. 7, # 1 p. 45 - 49

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被引用次数: 10

摘要

C6-Alkylthio-substituted purines have potential therapeutic applications such as in anticancer, antibacterial, and antiviral agents. For example, 4-nitrobenzylthioinosine (NBTI), which has been extensively studied in recent years, is a wellknown inhibitor for the equilibrative nucleoside transport protein ENT1(Figure 1).[1]