Abstract An investigation has been carried out into the Schlack-Kumpf reaction, ie, the reaction of amino acids with a mixture of acetic anhydride, acetic acid and sodium thiocyanate (occasionally ammonium thiocyanate was used). Particular emphasis was placed on the reactions with amino acids containing sensitive or functional side chains, ie, serine, threonine, arginine, proline, lysine, histidine, cysteine, and aspartic and glutamic ...