… and general synthesis of 2'-deoxy-C-nucleosides. Synthesis of 5-(2-deoxy-. beta.-D-erythro-pentofuranosyl) uracil,-1-methyluracil,-1, 3-dimethyluracil, and-isocytosine

K Pankiewicz, A Matsuda…

文献索引：Pankiewicz, Krzysztof; Matsuda, Akira; Watanabe, Kyoichi A. Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 485 - 488

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被引用次数: 69

摘要

(6d) were synthesized. Compounds 6b-d are C-nucleoside isosteres of thymidine, 2'- deoxyuridine, and 2 '-deoxycytidine, respectively. 1, 3-Dimethylpseudouridine (la), 1- methylpseudouridine (lb), pseudouridine (IC), and pseudoisocytidine (la) were treated with 1, 3-dichloro-1, 1, 3, 3-tetraisopropy~ isiloxane in pyridine to afford the corresponding 3', 5'- tetraisopropyldisiloxanyl derivatives 2 which were converted into the respective 2'-0-[( ...