Organic letters

Aromatic ortho-Benzylation Reveals an Unexpected Reductant

A Martins, M Lautens

文献索引：Martins, Andrew; Lautens, Mark Organic Letters, 2008 , vol. 10, # 21 p. 5095 - 5097

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被引用次数: 22

摘要

ABSTRACT The discovery of a novel arylpalladium (II) reduction enables the synthesis of diarylmethanes via reductive benzylation. Benzyl chlorides were found to be the major source of hydride, acting as an alkylating agent and an aprotic surrogate for benzyl alcohol. This represents the first example of an arylpalladium (II) reduction mediated by a benzyl halide.