The First Anti??Markovnikov Hydration of Terminal Alkynes: Formation of Aldehydes Catalyzed by a Ruthenium (II)/Phosphane Mixture

M Tokunaga, Y Wakatsuki

文献索引：Tokunaga, Makoto; Wakatsuki, Yasuo Angewandte Chemie - International Edition, 1998 , vol. 37, # 20 p. 2867 - 2869

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被引用次数: 204

摘要

Abstract With the right auxiliary phosphane ligands—for example, pentafluorophenyldiphenylphosphane or the sodium salt of 3, 3′, 3 ″-phosphinidynetris (benzenesulfonic acid)—the ruthenium (II)-catalyzed hydration of terminal alkynes to aldehydes proceeds by the previously unknown anti-Markovnikov addition of water [Eq.(a)]. Complexes of the type [RuCl 2 (PR 2 R 2′ R ″) x](R= alkyl, Ph) are discussed as ...