Process development and pilot-scale synthesis of new Cyclization conditions of substituted phenylacetamides to tetrahydroisoquinoline-2-ones using eaton's reagent
LG Ulysse, Q Yang, MD McLaws…
文献索引：Organic Process Research and Development, , vol. 14, # 1 p. 225 - 228
... the cyclization of phenylacetamides was broadened to understand the scope and limitation of the process. ... General Procedure for the Preparation of 6 Analogues N-Methyl phenylacetamide (10 mmol) in ... solution was extracted with EtOAc (2 × 20 mL), and the organic layer was ...
