Large-scale Negishi coupling as applied to the synthesis of PDE472, an inhibitor of phosphodiesterase type 4D

PW Manley, M Acemoglu, W Marterer…

文献索引：Organic Process Research and Development, , vol. 7, # 3 p. 436 - 445

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被引用次数: 46

摘要

... Organic Process Research & Development. ... This contribution describes the refinement of the research synthesis into a high-yield process, which was utilised in the ... 2.2.1. Large-Scale Synthesis of Intermediates 5 and 9. The high-yielding Green−Rowe oxidation procedure, 26-28 ...