Search for non-steroidal antiinflammatory drugs of the substituted thiopropionic acid class

BA Trofimov, AN Vavilova, SV Kalmykov…

文献索引：Trofimov, B. A.; Vavilova, A. N.; Kalmykov, S. V.; Kazimirovskaya, V. B. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 12 p. 987 - 989 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 12 p. 1463 - 1465

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摘要

The IR spectra (obtained on a" Specord-75" spectrophotometer in KBr pellets) of the ammonia salts of the alkylthioproprionic acids show broad and intense absorption maxima at 3300-2500 cm-1 (Vort), as well as at 1710 cm-1 (Vo-o), and at 1300-1140 cm-1 (C--<)--H group oscillation); the double bond was absent. Condensation of hexanethiol with the potassium salt of methacrylic acid occurred in the same manner to give the compound ...