Bulletin of the Korean Chemical Society

Convenient one-pot Synthesis of sulfonamides from thiols and disulfides using 1, 3-dichloro-5, 5-dimethylhydantoin (DCH)

H Veisi

文献索引：Veisi, Hojat Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 2 p. 383 - 386

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被引用次数: 5

摘要

Abstract A convenient synthesis of sulfonamides from thiols and disulfides is described. In situ preparation of sulfonyl chlorides from thiols is accomplished by oxidation with 1, 3- dichloro-5, 5-dimethylhydantoin (DCH) under Nbenzyl-trimethylammonium chloride and water. The sulfonyl chlorides are then further allowed to react with excess amine in the same reaction vessel.