Summary The synthesis of the title compounds is described. Some of the compounds prepared exhibited antimicrobial activity in vitro. Structure-activity relationship is briefly discussed. ... Hogberg et al. have found that the acid-catalyzed condensation of resorcinol with several aromatic aldehydes gave two stereoisomeric macrocycles of general struc- ture I [l]. The configurations and conformations of the two isomers were investi- gated using molecular models and symmetry ...