Abstract Synthesis of the title compounds has been achieved starting from 4-oxo-3, 4- dihydro-2H, 5H-thiopyrano [3, 2-c][1] benzothiopyran 6, 6-dioxide (III), which was converted to glyoxylate (IV), β-ketoester (V), difluoride complex (VII) and β-diketone (XII) gave with hydrazine, hydroxyl-amine and glycine ethyl ester several azadithiasteroid analogues.