A regiocontrolled synthesis of substituted indoles by palladium??catalyzed coupling of 2??bromonitrobenzenes and 2??bromoacetanilides

A Kasahara, T Izumi, S Murakami…

文献索引：Kasahara, Akira; Izumi, Taeko; Murakami, Satoshi; Miyamoto, Kazuhiro; Hino, Toshimi Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1405 - 1413

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被引用次数: 37

摘要

Abstract The palladium-catalyzed cross-coupling reaction of 2-bromonitrobenzenes or 2- bromoacetanilides with ethylene has been used to produce a variety of substituted indoles. The mild reaction conditions and selectivity inherent in the coupling reaction have been utilized to produce regiochemically pure 4-, 5-, 6-, and 7-substituted indoles.