A New Method for the Synthesis of Macrocyclic Peptides

JC Sheehan, WL Richardson

文献索引：Sheehan; Richardson Journal of the American Chemical Society, 1954 , vol. 76, p. 6329

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被引用次数: 24

摘要

Recently the syntheses of several cyclic tripeptides have been claimed. In two instances only amorphous products were~ btained.~.~ In a third case the cyclic peptide product was stated to be crystalline, although it consisted presumably of four stereoisomeric forms (two racemates), since it was obtained by heating glycyl-DL-alanyl-DL-phenylalanine methyl ester under reflux in a methanolic solution containing ammonia.? The cyclic peptide- ...