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Synthetic and structural studies of some chloro??substituted methyl 2, 1??benzisoxazole??3??carboxylates and related compounds

TJ Mccord, DR Smith, JK Swan…

文献索引:McCord,T.J. et al. Journal of Heterocyclic Chemistry, 1979 , vol. 16, p. 1249 - 1252

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被引用次数: 3

摘要

Abstract Methyl 5-chloro-and 5, 7-dichloro-2, 1-benzisoxazole-3-carboxylates have been synthesized by treatment of o-nitromandelic and 5-chloro-2-nitroamandelic methyl esters, respectively, with thionyl chloride under appropriate reaction conditions. The structural assignments of both heterocyclic products were based on elemental and spectral analyses, and their conversion to the corresponding 5-chloro-and 5, 7-dichloro substituted 2, 1- ...