Abstract Because acylurea and carbamate groups are associated with various pharmacological activities, a number of saccharin and 6-nitrosaccharin derivatives containing these groups were synthesized for pharmacological screening. The compounds prepared were: 2-(diethylcarbamoyl) saccharin; 2-(diethylcarbamoyl)-6-nitrosaccharin; 2- (diethylthiocarbamoyl) saccharin; and 2-carbethoxysaccharin. Also isolated from the ...