New class of mixed cuprate (I) reagents, lithium hetero (alkyl) cuprate (I), which allow selective alkyl group transfer

GH Posner, CE Whitten, JJ Sterling

文献索引：Posner,G.H. et al. Journal of the American Chemical Society, 1973 , vol. 95, # 23 p. 7788 - 7800

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被引用次数: 210

摘要

Abstract: Five different alkylhetero (alkyl) cuprate (I) and arylhetero (alkyl) cuprate (I) reagents of the form Het (R)-CuLi have been prepared from the corresponding heterocopper species (Het-Cu) and organolithium reagents (RLi): Het= t-BuO, PhO, t-Bus, PhS, Et2N. The stability of these mixed cuprate reagents follows the order PhS> PhO> t-BuO> t-Bus-Et2N. Of these five, PhS (R) CuLi is most effective for selective conjugate addition and substitution ...