Derivatives of Fluorene. XIX. 1, 2 9-o-Chlorocinnamylidenefluorene and Related Compounds

TL Fletcher, MJ Namkung, JR Dice…

文献索引：Fletcher,T.L. et al. J. Med. Chem., 1965 , vol. 8, p. 347 - 350

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被引用次数: 2

摘要

In screening sponsored by the Sational Service Center of the National Cancer Institute, activity against an animal tumor was discovered with a compound presumed (and first reported in 1919) to be 9-o-chlorobenzylidenefluorene. Upon examination, the compound has been found to be 9-o-chlorocinnamylidenefluorene which was produced in small yield as the only recognizable product in an attempted sodium ethoxide-ethanol condensation ...