Synthesis and Neurotropic Activity of (Heterylphenylmethyl)-Amines and-Ureas

…, VA Aleshina, SA Sukhanova, TI Kabanova

文献索引：Shamshin; Aleshina; Sukhanova; Kabanova Pharmaceutical Chemistry Journal, 2001 , vol. 35, # 7 p. 349 - 352

全文：HTML全文

被引用次数: 3

摘要

The antiepileptic drugs widely used in clinical practice, such as diphenin, phenobarbital, and benzonal, belong to the cyclic derivatives of urea [1]. Opening of the hydantoin ring between carbon in position 5 and nitrogen leads to a noncyclic urea derivative (a-diphenylacetylurea, known as the drug fenuron) still retaining the anticonvulsant properties [2]. In the search for new substances possessing neurotropic activity in the series of benzohydrylamines and ...