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Tetrahedron Letters

A convenient one-pot synthesis of polysubstituted pyrroles from N-protected succinimides

M Kobeissi, O Yazbeck, Y Chreim

文献索引:Kobeissi, Marwan; Yazbeck, Ogaritte; Chreim, Yamama Tetrahedron Letters, 2014 , vol. 55, # 15 p. 2523 - 2526

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被引用次数: 6

摘要

Abstract The dienamine products formed by the reaction between polysubstituted succinimides and the Petasis reagent were subjected to isomerization under mild acidic conditions to give polysubstituted pyrroles in excellent yields (85–95%). The scope and limitations of this methodology are explored.