Medicinal chemistry research

In vitro bacteriostatic and DNA interaction studies of drug-based mixed-ligand complexes of cobalt (II)

M Patel, M Chhasatia, B Bhatt

文献索引：Patel, Mohan; Chhasatia, Mehul; Bhatt, Bhupesh Medicinal Chemistry Research, 2011 , vol. 20, # 2 p. 220 - 230

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被引用次数: 13

摘要

Abstract The dinuclear cobalt (II) complexes with ciprofloxacin and bidentate ligands were synthesized and characterized using infrared spectra, electronic spectra, magnetic measurements, elemental analyses, thermal investigation, and mass spectroscopy. Here in we tried to increase an antibacterial activity of ciprofloxacin drug due to formation of mixed- ligand complexes. Synthesized compounds were found to be more potent compared to ...