The proline-catalyzed direct asymmetric three-component Mannich reaction: scope, optimization, and application to the highly enantioselective synthesis of 1, 2-amino …

B List, P Pojarliev, WT Biller…

文献索引：Morita; Nagasawa; Yahiro; Matsunaga; Kunieda Organic letters, 2001 , vol. 3, # 6 p. 897 - 899

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被引用次数: 638

摘要

... Volume: Page: ... new synthetic methods for the construction of nitrogenous molecules has defined the frontiers of organic synthesis since ... results (Table 1). Reacting three different ketones (butanone, methoxyacetone, and hydroxyacetone, each 20 vol %) with p ...