Synthesis of 2-arylpropionaldehydes through hydroformylation

D Neibecker, R Reau, S Lecolier

文献索引：Neibecker, Denis; Reau, Regis; Lecolier, Serge Journal of Organic Chemistry, 1989 , vol. 54, # 22 p. 5208 - 5210

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被引用次数: 47

摘要

Now that 2-arylpropionic acids are commonly used as antiinflammatory drugs,'there is much interest in their simple and economic synthesis. 2 Recently, Riley and co-workers3 reported an efficient method based on the oxidation of the corresponding 2-arylpropionaldehydes using manganese stearate as oxidizing agent and m-chloroperoxybenzoic acid as catalyst initiator. The major preparations reported for these aldehydes start from aryl olefins4 or ...