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Water Encapsulation in a Polyoxapolyaza Macrobicyclic Compound

P Mateus, R Delgado, P Groves…

文献索引:Mateus, Pedro; Delgado, Rita; Groves, Patrick; Campos, Sara R. R.; Baptista, Antonio M.; Brandao, Paula; Felix, Vitor Journal of Organic Chemistry, 2012 , vol. 77, # 16 p. 6816 - 6824

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被引用次数: 5

摘要

A new heteroditopic macrobicyclic compound (t2pN5O3) containing two separate polyoxa and polyaza compartments was synthesized in good yield through a [1+ 1]“tripod–tripod coupling” strategy. The X-ray crystal structure of H3t2pN5O33+ revealed the presence of one encapsulated water molecule accepting two hydrogen bonds from two protonated secondary amines and donating a hydrogen bond to one amino group. The acid–base ...