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4-Anilino-6, 7-dialkoxyquinoline-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6, 7- …

A Wissner, DM Berger, DH Boschelli…

文献索引:Journal of Medicinal Chemistry, , vol. 43, # 17 p. 3244 - 3256

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被引用次数: 178

摘要

... Journal of Medicinal Chemistry. ... 17 Several pharmaceutical firms, 18 including ourselves, 19 established programs based on these inhibitors, and now at least three such compounds have entered or will be entering clinical trials. ...