Copper??Catalyzed Azide–Alkyne Cycloaddition in the Synthesis of Polydiacetylene:“Click Glycoliposome” as Biosensors for the Specific Detection of Lectins

…, M Assali, I Fernández, N Khiar

文献索引：Leal, Manuel Pernia; Assali, Mohyeddin; Fernandez, Inmaculada; Khiar, Noureddine Chemistry - A European Journal, 2011 , vol. 17, # 6 p. 1828 - 1836

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被引用次数: 28

摘要

Abstract Supramolecular self-assembly of conjugated diacetylenic amphiphile-tethered ligands photopolymerize to afford polydiacetylene (PDA) functional liposomes. Upon specific interaction with a variety of biological analytes in aqueous solution, PDA exhibits rapid colorimetric transitions. The PDA nanoassemblies, which are excellent membrane mimics, include an ene–yne polymeric reporter responsible for the chromatic transitions ...