Synthetic communications

Simple synthesis of versatile coumarin scaffolds

L Polito, M Cravini, L Poletti, L Lay

文献索引：Polito, Laura; Cravini, Massimiliano; Poletti, Laura; Lay, Luigi Synthetic Communications, 2006 , vol. 36, # 15 p. 2203 - 2209

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被引用次数: 15

摘要

Abstract We describe an approach using ring??closing metathesis (RCM) to synthesize versatile coumarin derivatives that present appropriate substitutions both at the aromatic and at the α, β??unsaturated lactone ring. The obtained compounds can be used as molecular scaffolds suitable for further diversifications through a combinatorial approach.