Gold (I) mediated Meyer–Schuster rearrangement for the installation of the 'lower'side chain of prostaglandins and their analogs has been developed. This Au-mediated rearrangement, featuring a low catalyst loading and mild reaction conditions, has been demonstrated to be an efficient alternative to the standard Horner–Wadsworth–Emmons reaction in prostaglandin chemistry. Moreover, the present results provide a new synthetic process ...
![(3aR,4R,5R,6aS)-六氢-2-氧代-4-[(1E)-3-氧代-5-苯基-1-戊烯基]-2H-环戊并[b]呋喃-5-基 [1,1’-联苯]-4-甲酸酯结构式](https://image.chemsrc.com/caspic/473/41639-72-9.png)
