前往化源商城

Total syntheses of KS-501, KS-502, and their enantiomers

RG Dushin, SJ Danishefsky

文献索引：Dushin; Danishefsky Journal of the American Chemical Society, 1992 , vol. 114, # 2 p. 655 - 659

全文：HTML全文

被引用次数: 77

摘要

Abstract: The total syntheses of the title compounds are described. The key step involves the coupling of the anhydrofuranose 18 (as well as its enantiomer) with salicylate derivative 17 under the influence of potassium carbonate. Both the epoxidation of 7 (achieved with 2, 2- dimethyldioxirane) and the glycosylation of 17 appear to be stereospecific.

 相关合成线路
2,2-dimethyl-5-(1-heptyl)-7-hydroxy-4H-1,3-benzodioxin-4-one结构式

137571-77-8

2,2-dimethyl-5-...

~97%

5-庚基苯-1,3-二醇结构式

500-67-4

5-庚基苯-1,3-二醇

查看详情
1-庚炔结构式

628-71-7

1-庚炔

~%

5-庚基苯-1,3-二醇结构式

500-67-4

5-庚基苯-1,3-二醇

查看详情
2,4,6-三羟基苯甲酸结构式

83-30-7

2,4,6-三羟基苯甲酸

~%

5-庚基苯-1,3-二醇结构式

500-67-4

5-庚基苯-1,3-二醇

查看详情
5,7-二羟基-2,2-二甲基-4H-1,3-苯并二噁烷-4-酮结构式

137571-73-4

5,7-二羟基-2,2-二甲基...

~%

5-庚基苯-1,3-二醇结构式

500-67-4

5-庚基苯-1,3-二醇

查看详情
7-(Benzyloxy)-5-hydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one结构式

137571-74-5

7-(Benzyloxy)-5...

~%

5-庚基苯-1,3-二醇结构式

500-67-4

5-庚基苯-1,3-二醇

查看详情
未登录结构式

137571-76-7

未登录

~%

5-庚基苯-1,3-二醇结构式

500-67-4

5-庚基苯-1,3-二醇

查看详情
7-(benzyloxy)-2,2-dimethyl-5-[(trifluoromethyl)sulfonyl]-4H-1,3-benzodioxin-4-one结构式

137571-75-6

7-(benzyloxy)-2...

~%

5-庚基苯-1,3-二醇结构式

500-67-4

5-庚基苯-1,3-二醇

查看详情
未登录结构式

137571-85-8

未登录

~99%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
1-庚炔结构式

628-71-7

1-庚炔

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
2,4,6-三羟基苯甲酸结构式

83-30-7

2,4,6-三羟基苯甲酸

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
5,7-二羟基-2,2-二甲基-4H-1,3-苯并二噁烷-4-酮结构式

137571-73-4

5,7-二羟基-2,2-二甲基...

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
7-(Benzyloxy)-5-hydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one结构式

137571-74-5

7-(Benzyloxy)-5...

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
未登录结构式

137571-76-7

未登录

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
7-(benzyloxy)-2,2-dimethyl-5-[(trifluoromethyl)sulfonyl]-4H-1,3-benzodioxin-4-one结构式

137571-75-6

7-(benzyloxy)-2...

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
benzyl 2-heptyl-4,6-dihydroxybenzoate结构式

94693-37-5

benzyl 2-heptyl...

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
2,2-dimethyl-5-(1-heptyl)-7-hydroxy-4H-1,3-benzodioxin-4-one结构式

137571-77-8

2,2-dimethyl-5-...

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
1,4-anhydro-3-O-benzyl-5,6-cyclopentylidene-2-deoxy-L-lyxo-hex-1-enofuranose结构式

137571-72-3

1,4-anhydro-3-O...

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情
未登录结构式

137571-80-3

未登录

~%

4-[2-[(2S,3R,4R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-6-heptyl-4-hydroxybenzoyl]oxy-2-heptyl-6-hydroxybenzoic acid结构式

120634-85-7

4-[2-[(2S,3R,4R...

查看详情

首页 |  期刊大全 |  MSDS查询 |  化工产品分类 |  生物活性化合物 |  关于我们 |  免责声明:知识产权问题请联系 service1@chemsrc.com
Copyright © 2026 ChemSrc All Rights Reserved