N-(Aminoacyl) and N-(aminoalkyl) derivatives of 4-cyclopentylaniline and N-ethyl-4-cyclopentylaniline; Synthesis and pharmacological screening

Z Vejdělek, M Bartošová, M Protiva

文献索引：Vejdelek; Bartosova; Protiva Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 1 p. 156 - 162

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被引用次数: 3

摘要

Abstract Acylation of 4-cyclopentylaniline (I) with chloracetyl chloride, 3-chloropropionyl chloride, 4-chlorobutyryl chloride and 2-bromo-4-methylvaleryl bromide gave the halogenoacyl derivatives IV-VII out of which the first two were subjected to substitution reactions with diethylamine and piperidine. The N-(aminoacyl) derivatives VIII-XI obtained were reduced with lithium aluminium hydride to the N-(aminoalkyl) derivatives XII and XV. ...