European Journal of Organic Chemistry

2??Substituted Benzo [b] furans from (E)??1, 2??Dichlorovinyl Ethers and Organoboron Reagents: Scope and Mechanistic Investigations into the One??Pot Suzuki …

LM Geary, PG Hultin

文献索引：Geary, Laina M.; Hultin, Philip G. European Journal of Organic Chemistry, 2010 , # 29 p. 5563 - 5573

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被引用次数: 18

摘要

Abstract 2-Substituted benzo [b] furans can easily be assembled from simple phenols, boronic acids or other organoboron reagents, and trichloroethylene. The overall process requires only two synthetic steps, with the key step being a one-pot sequential Suzuki cross- coupling/direct arylation reaction. The method tolerates many useful functional groups and does not require the installation of any other activating functionality. The modular nature of ...