Chemical Communications

A general and efficient approach to 2 H-indazoles and 1 H-pyrazoles through copper-catalyzed intramolecular N–N bond formation under mild conditions

J Hu, Y Cheng, Y Yang, Y Rao

文献索引：Hu, Jiantao; Cheng, Yongfeng; Yang, Yiqing; Rao, Yu Chemical Communications, 2011 , vol. 47, # 36 p. 10133 - 10135

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被引用次数: 48

摘要

A new efficient copper-catalyzed intramolecular amination reaction has been developed to readily synthesise a wide variety of multi-substituted 2H-indazole and 1H-pyrazole derivatives from easily accessible starting materials under mild conditions. A highly selective ligand for estrogen receptor β was prepared in three steps by employing this method.